The role of statins in chronic heart failure
نویسندگان
چکیده
PURPOSE OF REVIEW To discuss unresolved issues and recent findings regarding the use of statins in heart failure. RECENT FINDINGS Recent data from Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico--Heart Failure and Controlled Rosuvastatin Multinational Trial in Heart Failure suggest that statins did not have any effect on outcome despite significant reduction in low-density lipoprotein and high sensitivity C-reactive protein. SUMMARY Most of the evidence for the use of statins in heart failure originates from retrospective trials and post-hoc analyses, and is not supported by prospective randomized clinical trials. There is no evidence to support initiating statin therapy in patients with symptomatic New York Heart Association II-IV heart failure, regardless of the cause.
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عنوان ژورنال:
دوره 11 شماره
صفحات -
تاریخ انتشار 2009